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Because comic dialogue is textual, I will rely on punctuation and word balloon design to get across voice inflection. This is a perfect example of the same remark in two different tones for two different reactions.

The CRO pest houses are predominantly existing structures that are commandeered and retrofitted to suit the needs of the organization and patients. The scaffold and tarp surrounding is something I was inspired to add from the game The Division, which despite being a total narrative and thematic mess has some really incredible design work.You can see a lot of external wiring and ventilation, intended to emphaisze the ad hoc, improvised nature of the operation while also creating an ugly and intimidating appearance. These are measures thrown together in a big hurry with whatever was available or could be obtained with function first and aesthetics last.The armed guards patrolling what is ostensibly a hospital are the finishing touch on this  scary place - meant more to keep patients in than invaders out, but I'd imagined that jailbreaks with outside assistance were not unheard of.

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Bill Lemmond

Thanks for putting so much thought into everything. :)