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That's...

That's science! AND ALSO HIGHLY ILLEGAL AND IMMORAL 

Sketch for HarmlessKitten.

Explanation: Sodium Thiopental is a fast acting Anesthetic, that makes users feel calm, secure, and most importantly, Compliant. Which Twiggles wants. 

But It needs to get to the brain to take effect. And since Twilight can't just syringe Applejack with a shot of drugs, she's trying to sneak it into apples. 

BUT ALSO stuff you eat doesn't just go straight to your brain. In fact, there's a Blood-Brain Barrier preventing exactly that. So to bypass that shit, Twilight is sneaking the drug through via a Peptide Agent which carries the Sodium Thiopental through the membrane.

And Then [Science 88/90]: the peptide agent Science Science Magic

EXPLOSION

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Comments

Pshyzo

THEY'RE PUTTING CHEMICALS IN THE APPLES THAT TURN THE FRIGGIN EQUESTRIA GIRLS GAY

JPMK! {verb}

This panel was unethducational! :D

TwilightIsMagic

I have a few suggestions for Twilight right now, as it so happens... I hope she listens~