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Hey everyone,

No, we have not bumped our planned Jaron Lanier episode again.

Yes, we do have another episode planned. This Friday we will record an interview with Gideon MK (the Health Nerd on Twitter: https://twitter.com/GidMK) on the recently published TOGETHER trial and more broadly dealing with Ivermectin advocates/the anti-vaccine community.

We are going to use some clips to illustrate relevant points and give Gideon some jumping off points. 

No obligations... but if anyone watches the above and has any particularly juicy parts or just questions they think we should answer I would appreciate a note (with a timestamp).

I'm going to be extracting quotes anyway, so no-one else should have to inflict this on themselves... but if you were interested and watching anyway, suggestions are welcome. 

If you have other questions you would like answered also open to suggestions!

We will post the unedited interview on Friday.

Files

Cold Confusion: Alexandros Marinos unpacks the TOGETHER Trial with Bret

Sign up for the Spectator at: https://spectatorworld.com/specialoffer/ Use code: DARKHORSE Farrow SkinFood is lard-based skincare that nourishes the skin without preservatives or added chemicals. Go to http://farrow.life/darkhorse for 20% off your first purchase; additional 15% off with a recurring subscription. ***** Bret speaks with Alexandros Marinos, who has analyzed the TOGETHER trial, which aims to identify effective repurposed therapies to prevent the disease progression of COVID-19. Alexandros is the Founder/CEO of http://balena.io & aspiring practical philosopher. Find him on: https://twitter.com/alexandrosm https://doyourownresearch.substack.com/ Mentioned in this episode: https://www.togethertrial.com/ https://doyourownresearch.substack.com/p/the-problem-with-the-together-trial ***** Find Bret Weinstein on Twitter: @BretWeinstein, and on Patreon. https://www.patreon.com/bretweinstein Please subscribe to this channel for more long form content like this, and subscribe to the clips channel @DarkHorse Podcast Clips for short clips of all our podcasts: https://www.youtube.com/channel/UCAWCKUrmvK5F_ynBY_CMlIA All removed videos can be found on Spotify Video and Odysee: https://open.spotify.com/show/57R7dOcs60jUfOnuNG0J1R https://odysee.com/@BretWeinstein:f Check out the DHP store! Epic tabby, digital book burning, saddle up the dire wolves, and more: http://www.store.darkhorsepodcast.org Theme Music: Thank you to Martin Molin of Wintergatan for providing us the rights to use their excellent music. ***** Timestamps: (00:00) Introduction (03:11) Better Skeptics project – analyzing COVID podcasts (08:12) TOGETHER trial and its timeline (15:35) Ads (19:08) Dosage & initial TOGETHER trial design (25:29) Confusing paper and placebo group dropout? (31:23) IVM dose too low and new protocol (35:04) Trial recruitment over time and key 10-week period (43:42) Systemic errors (51:33) Placebo arm from earlier period? (57:11) Trial data not being released (01:02:27) Exclusion criteria flipped (01:06:38) Hypothesis on algorithm rebalancing arms (01:13:35) Allocation to Fluvoxamine arm (01:17:12) TOGETHER trial authors believe IVM has an effect (01:20:15) Credible intervals and Bayesian statistics (01:25:55) Will we ever get the full story? (01:30:28) Dosing and weight limit (01:34:52) Background use of IVM in Brazil (01:47:19) “Independent” committee monitoring trial (01:54:29) Cavallo study and inconsistency in response (01:57:41) Press releases and cold confusion (02:09:27) Wrap up

Comments

Kyle Wilson

Excited for this. These are two of the most loathsome people imaginable and I need this episode as a cathartic release

Tim Tripp

I tried to listen to these two but gave up. I gather Brett does not listen to TWIV or he does but his galaxy brain makes him the ultimate judge of naughty or nice studies. Experts schmexperts.

Jason Trock

Oof I’m an hour in. Very painful. Bad sciencing indeed.

Conal dunn

I’m glad you’ll watch this for us. I started and gave up. Brett really is a loathesome bastard and I wonder what really went on at that uni that kicked him out.

Jeanne H-B

I, too, gave up. Thanks for taking on the hours of listening to so much smug, awful content. Looking forward to Gideon and y’all critiquing this mess.

Jesse Hodges

I am SO EXCITED about this. I'm sure it will make me sick to my stomach, but I'm still excited.

Dan

Wow, interesting that Alexandros says he’s “close” to 120kg (265lbs) (21:45) Unless he’s 6 ft 7”tall…this man is OBESE. Wasn’t he cheering on B&H when they were claiming everyone should just lose weight to protect against COVID instead of getting vaccinated (paraphrasing)? Also, a single dose of 400mcg/kg of IVM is NOT “a dose we might consider homeopathic” (19:49). 150-200mcg/kg single dose is the ONLY dose FDA approved dose for IVM (for parasitic infections)…so no Alexandros, double the FDA approved dosing for a medication is not “homeopathic”. Goes to show how bonkers high the FLCCC set their dosing with ZERO legit prior safety data for that dosing.

Dan

(24:15) Bret thinks that IVM taken on an empty stomach stays in the gut and doesn’t get absorbed into the body….because Bret thinks ALL parasite infections are in the gut. Guess what parasite has ZERO Gastrointestinal component to its life cycle….Ding ding ding Onchocerciasis (River Blindness)…one of the main uses of IVM! https://www.cdc.gov/dpdx/onchocerciasis/index.html

Dan

Also people who think that they can design and execute perfect clinical/research trials in the real world (not in a computer simulation or in one’s imagination) have clearly had zero actual experience in real clinical trials/research

Robert Andrews

Trying to watch this. I almost feel sorry for Alexandros at how, during his big moment, Bret keeps interrupting him to give his own gloss, because AM is not really that good at it, and maybe doesn't always toe the line.

Robert Andrews

The Spectator is now advertising with them??? Is this Murray's doing?