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Content

Hey everyone,

Sorry this one took so long.

Matt and I had deadlines and all the usual academic guff that gets in the way.

The episode will come out on the main feed later today but since it is ready in audio format now. I thought you might appreciate it a few hours early.

Any audio issues let me know and I'll try and fix before we release on the main feed.

Comments

Lillie

Thank you!

Anjan Sarkar

Excited to see what the Gurumeter has to say. Hubey might make it spin .....

LaserRange

Really looking forward to his one. Thanks lads.

Ymirsdreams

I will add this to my podcast listening protocol.

Emma

I think a missing piece of the puzzle, when speculating on why Attia was so ready to self experiment with metformin etc. Is that Peter has said that when he was younger he used to struggle with his weight. My theory on him is he is a smart guy obvs but I think he has orthorexia. And I think this messes with his thinking when it comes to his own body. And yes he had chops at reading science papers. But I worry in a lot of ways he's just a male Gwyneth Paltrow. In that he has disordered behaviour around food and exercise and he's influencing his followers to adopt similar disordered behaviours.

billw2011

I always thought the intro music sounded like the HHGttG, glad to know its intentional as its a great theme.

Lee Kebum

Halfway through. This Matt Foreman fellow seems like he's got things figured out!

Artemis Green

What's more torturous: Vogon poetry or Brett Weinstein's 'logic'?

Colin Fardey

RE the intro . The coversation about the relationship between North and South was interesting . I can honestly say , I have never heard of anyone down here holding a negative opinion about people from the North . Worst I heard would have been a comment about the accents maybe.

Artemis Green

For real, am I listening to someone say they did '18 months of intensive work with a psychiatrist' so that they could have 'the most profound dream ever' at a conference in Aspen?? Re: Matt saying 'Australians don't have revelations like that', regrettably I must beg to differ. But the ones who do all live in Byron or Bondi so fortunately the rest of us don't have to hear about their dreams.

Linda Sears

Thank you. I’ll be late to listening since a new stack of papers just came in. This will be my reward after I’m done.

Subodh Kafle

Even if the findings of the paper were real, does it have profound medical implications? You reduce a kid's ADHD medicine dose while telling them it's still the same. Their body responds as if the dose was unchanged. Is the paper/Huberman asserting that negative side effects will be weaker while positive effects stay the same? I can't see how this would matter unless you're in a country where medication has to be rationed.

Ben Godek

Thinking of fitness optimization as these guy's hobby definitely helped me understand them. Some people memorize all the stats from the NFL, some people build model trains, and some people spend all their mental energy thinking about which supplements and fitness routines to adopt. I doubt they'd admit this, but I bet they enjoy the process of tinkering with their health just as much, if not more than, the positive health outcomes themselves.

Christoph

This made me think about the relationship between different values and motivations and approaches to science. Hooverman seems to be high on technically exploitable causalities (for biohacking). Others get nerdy on methodological correctness, the impractical complexity of the world or epistemological questions. Prioritizing usefulness seems the most obviously problematic approach, but it's probably about finding a good balance. Focusing too heavily on any one of the aspects will lead to shortcomings. So, maybe people like the biohackers are not just cooky hobbyists but provide a necessary tension to the scientific endeavor - however grating that might be to those differently inclined ;)

Jim Murray

Really great listen, thanks guys. I'm interested in any insight you can offer on the issues someone like Huberman might experience at an academic institution given the popularity of his podcast (as well as the type of audience he attracts). Do you think his colleagues take him less seriously because of it? As you say, he seems to go to great lengths to not comment on covid vaccines. If he did start giving anti-vaccine type advice, how much of an impact (if any) would that have on his academic work and his professional relationships?

Bath Cat

“You have to play with the play dough that’s available, not your dream play dough.”

YellowDreams

More pronunciation fun this time from Chris with longevity with a hard g 😛

Robert Andrews

Love the podcast, but I felt that this one was less "Decoding the Gurus" and more "Embodying Reviewer 2". :D

Jenny

In the clips when you hear Brett Weinstein talking, he's still coughing a LOT. Maybe he should have gotten that vaccine!

brianshmrian

I don't want to be a Huberman apologist, but wasn't he suggesting that belief in a vaccine _dosage_ might affect immune response? He wasn't saying that you could visualize an antigen in order to create antibodies. The dose has to be greater than 0.

Martin Pelchat

Great episode, once again. As a regular listener of the Huberman podcast and Peter Attia's podcast, I was eagerly awaiting you guys to cover this journal club. I am the first to admit that I probably fall into the mould of the typical 'optimizer': I watch what I eat, I am a fitness enthusiast, etc., though I am not at the Attia/Huberman extreme of ingesting 100 supplements per day. I am well aware of the absurdity of health optimization and I've heard Attia and Huberman (and Tim Ferris) being able to take a step back and not take themselves TOO seriously in their quest to live 'optiomally' to 150 years old. Matt made a good point: it is kind of like a hobby for people like me, and I am sure there are deeply rooted reasons for the crowd of optimizers to purse this quest, like an unconscious way to deal with existential questions, fear of death, etc. I find it quite disappointing to see that an 'academic' like Huberman, who claims that "science" is at the heart of his show, manages to wildly misinterpret research papers. It is frustrating for people like me who aren't specialists in the fields he covers, and who don't have time to delve into the research he cites to back up his claims, that he misrepresents the truth. I am sure that he does not do this willingly, and I know that he doesn't do this the majority of the time, but still, it is both sad to see that and great that you guys debunk some of the BS he puts out there. He is a very good communicator though, which is probably part of the reason for his popularity. About the 'flexing' Attia and Huberman did during one part of the episode: having listened to many episodes of Attia's podcast, he is (probably unconciously) the worst culprit of this - he often throws around medical acronyms or complex physiological mechanisms where he seems assume that the lay public (like me) will understand. I do think he knows his stuff quite deeply, and he probably doesn't do this counciously, but still it can be annoying at times. Anyway, always a pleasure listening to you guys! Great work.

Paul Bowman

Very enjoyable. I have to say they reminded me of the Mulder and Scully of the bro-science wellness world. Huberman's "I want to believe" finds its foil in Attia's more orthodox scepticism. But like Scully, his avowed scepticism is in the end supportive, towards a common project. Attia's orthorexia sounded a little alarming. Like you say, its not anyone's place to psychologise people's obsessions, whether body-building, extreme piercing, base-jumping or extreme S&M (between consenting adults). That said, anorexics would also argue that their's is just a lifestyle choice and they should be left to get on with it, so, hum... It does seem a little like a male gendered cousin - brorexia, maybe?

Liz Tily

Deer hunting with a bow. While I’m grounding to the earth. Next to a stream for the ions. 🙄 Optimizing guys, don’t knock it.