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INTRO

Incredible CRISPR breakthrough... note approximately 589 million adults (ages 20–79) are living with diabetes worldwide—about 1 in 9 adults. Considering how bad the food is, this is expected to explode to nearly 1BN people by 2050!

DETAILS

Diabetic Man With Gene-Edited Cells Produces His Own Insulin—No Transplant Drugs Required

A 42-year-old man with type 1 diabetes is once again producing his own insulin without immunosuppressive drugs following a CRISPR transplant. Researchers from Sweden and the US edited pancreatic cells in a targeted manner: they removed HLA antigens for foreign recognition and strengthened the immune-suppressing CD47 protein. Four months after the procedure, the modified cells are working without rejection.

The study, published in the New England Journal of Medicine, demonstrates for the first time a functioning alternative to lifelong immunosuppression in organ transplants. Although only a proof-of-concept with a low cell dose, this approach opens up revolutionary prospects for the permanent cure of type 1 diabetes without the risks of conventional rejection drugs, such as increased susceptibility to infection.

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Comments

This thing is sooo scarce!

Misleading this a potential cure for type 1 diabetes (lack of insulin producing cells) it type 2 (insulin resistance)

CryptoFarmer

This is amazing! I was diagnosed with type 1 diabetes 2.5 years ago at the age of 36

Solana Salad

Watch all the people involved disappear...

lee

I have type 2...

lee

Im on metformin, Jardine and ozempic to help control my type 2 :( so far I have been able to go from 4 metformin to 1.. its hard

Hobbit

Wow. Phenomenal. Proof of gene-edited cells evading the immune system means a plethora of gene-editing treatments are on the horizon.

InternetExploder

I think it's interesting 🤔 that this celebrates a gene-edited cell transplant treatment (I agree), while other times there have been clear antivax vibes here. Which, mind you mRNA makes you "print" some proteins temporarily but doesn't alter DNA.

Adam Toth

I was hoping they would just fix his own pancreas/immune system with gene editing. Still a big leap forward though.

Cobra350

Diabetes almost killed me at 6 years old in 1983. Fell into coma in kindergarten and the teacher rushed me to the hospital (can’t do that anymore). Was in coma for 6 days. My parents said doctors did not know if I would wake up. Grateful for having a wonderful K-teacher and the care of my doctor and nurses. Just sharing my experience with this serious illness.

dean2012ad

This is an astounding step in science.