NOVOCAINE...CANCELLED?? (Patreon)

Yes, the novocaine synthesis has been cancelled...but WHY? Well, as many of you know, I like to keep things legal when it comes to chemistry, on or off YouTube. Edgy maybe, but undeniably legal. If it has actual potential for legal ramifications, even if the potential is minimal, I tend to avoid it (hence why you won't see me making things that I would otherwise love to play with, like the not-so-binary explosives).

I thought making novocaine would be legal, since it's not a scheduled drug like amphetamine or DMT. However, non-scheduled doesn't mean non-controlled, and apparently, novocaine is prescription-only. Benzocaine? Nope, perfectly fine. Propylhexedrine (my "legal meth", which you can actually get high off, if your dumb)? Buy it off-the-shelf at Walmart! But novocaine? I guess you need doctor approval. Would the FDA or anyone ever take action over me making a few grams? I REALLY doubt it. But, if someone ever gets butt-hurt, they could theoretically charge me, and I'd rather avoid that.

This is probably for the best, honestly. I DID try to make it, just yesterday in fact, but the reaction was pretty ugly. Following a patent, I mixed the Butamben (butyl p-aminobenzoate) I made with my DEAE (diethylaminoethanol), along with a tiny bit of sodium methoxide in methanol, and heated the mix over a boiling water bath under vacuum. This was supposed to be a transesterification, leading to a nice blob of molten novocaine, but all I got was a bright yellow solid. I guess I could try to work it up and see if I got anything, but now I have a reason not to lol.

So, where do we go from here? Well, I COULD made a different analog that isn't controlled and actually behaves a lot like the much more illegal cocaine: dimethocaine. All I'd need to do is buy some neopentyl glycol off eBay, convert it to 3-chloro-2,2-dimethylpropanol, and basically perform the same reaction, reacting it with diethylamine instead of the 2-chloroethanol needed for novocaine (I'd probably follow a slightly different route though, since transesterifications apparently hate me). But, I don't have a use for dimethocaine (I'm sure as hell not snorting it lol), and I don't have information on the ingredients or process, so it'd be a big shot in the dark.

There are other drugs I could use diethylamine to make, such as coramine (nicotinic acid diethylamide, aka nikethamide, a heart/respiratory stimulant and banned performance enhancer) but we'll see what happens...I've got a lot to figure out. As of now, coramine looks like a pretty good bet: just have to make some methyl nicotinate from niacin (a basic esterification) and then react it with diethylamine to get the nicotinic acid diethylamide. This is better than using either nicotinoyl chloride (hard to make and requires toxic thionyl chloride) or nicotinic acid directly (might not even work, but would require high temperatures), so we'll see what happens!