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The Skeptics Guide #726 - Jun 08 2019 (Ad Free) (Patreon)

Published:
2019-06-08 16:56:27
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2026-06
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Content

Forgotten Superheroes of Science: Anne Dagg; News Items: WHO and TCM, Solar Cell Defect Solved, Mutation Affects HIV and Flu, Defense Lasers; Who's That Noisy; Your Questions and E-mails: Closest Planet; Science or Fiction 

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Comments

Jean-Marc Neuhaus

CCR5 mutated babies: not 1 novel mutation, but 4! Mutation by CRISPR/Cas relies on mutagenic repair of a double-strand break, usually causing knock-out. This means that each cut double-strand is independently mutated, so the 2 babies carry 4 independent (different, probably KO) mutations, each having unforseeable consequences.

Jean-Marc Neuhaus

By the way I disagree that germline manipulation is the only way to get rid of genetic diseases. Selective abortion or selective implantation of in vitro fertilized eggs is very efficient, as demonstrated in Greece (and Cyprus), where cases of thalassaemia have decreased by a factor 8 since the seventies. This is applicable to all recessive or dominant genetic diseases.