Possible sponsorship deal (Patreon)

I have just been offered a very tempting deal from Great Courses Plus (https://www.thegreatcoursesplus.com).  The deal is that they pay me to include a short advert for their on-line lecture courses in one/some of my videos.

As you can imagine,  I get offers all the time to place advertisements of various sorts in my videos, but so far I have resisted.  One reason I have resisted is that the adverts were for things so unrelated to my channel that they were often ridiculous (one was for a brand of shampoo!).  This one, though, is different.  My viewers are the sort of people who like watching videos on-line and perhaps learning about history, and this company does learning videos on-line, many of which are about history, so it is tricky to imagine ever getting a more relevant sponsor.  

I would put the advert towards the end of a video, and it would last in the region of thirty seconds, which would be skippable.  

But, I wonder, would this annoy my patrons greatly?  I would rather have your consistent and enthusiastic support than money from commercial sponsors.  On the other hand, the money I am being offered is very substantial - about ten times what I would normally get for a video.   

So, I am consulting you, the people who count most to me, before making a decision on this one.

Lloyd