Week 77! (Patreon)

This panel is from comic 212 titled Innuendo, which takes place during the tail end of the eleventh arc involving characters pairing up to do a research paper, including Kale and Campy as well as Bruce and Connor, who you'll recall as the ones screaming at each other in the above panel. It (or rather the whole sequence of Max's reactions) was suggested by Akuma.

This arc was probably where the comic was at peak popularity due to the whole business that was going on with Campy (if you'll recall the famous kiss Campy and Kale had in comic 200), but the whole thing between Bruce and Connor was a pretty important part of that arc as well. The two are both very flawed individuals, in different ways that end up actually resulting in similar consequences. Both cling to Campy and effectively want him to themselves, thus both are rather selfish and dependent. For Bruce it's because he's very obviously selfish and egotistical, wanting Campy because he thinks he deserves him more, knowing him longer and being his best friend. For Connor, though, it's because he's more reserved and needy emotionally, wanting Campy because he'd devoted himself to Campy for comfort and company. While presenting in different ways, the two express basically the same selfishness and effective objectification of Campy, and that combined with just your regular stresses of teenage romance is what causes Campy's stress and questioning of his relationships in the first place. I've always said I wanted to present more "realistic" relationships and such in the comic than you'd see elsewhere, and this was one of my attempts to do so, two different kinds of relationships involving overly-clingy people pulling someone apart emotionally. 

That all has more to do with the arc in general rather than just the panel, mostly because the only real info behind this comic/panel was adding in the joke that it sounded to Max that his son was engaging in homosexual activities through screamed double entendres. Also was a way to get Campy over to them from Kale to interrupt the prophesied kissing and to bring everything to a head and such.