【TL；DR】COVID19-SAR2 源頭之謎 (Patreon)

01，其實疫情一開始，就己經有人提出：「會唔會係武漢病毒研究所泄漏呀？」當時，神奇國度嘅中央政府就 spin 話係一日最衰都係啲人食野味。呢個 spin 好易令人信，因為大家都已經接受咗，某啲人嘅飲食文化係比較「開放」。

02，研究病毒呢一個行頭好窄；所以，如果真係涉及人為錯誤，所講專家嘅言論，亦好可能受到切身關係同利益嘅影響。

03，2020年2月19日，一班病毒研究員聯署，響 Lancet 刊登聲明：「強烈譴責一切懷疑病毒唔係源於大自然源頭嘅陰謀論。（We stand together to strongly condemn conspiracy theories suggesting that COVID-19 does not have a natural origin）」嘩，係咪似曾相識嘅口吻呢？

04，負責起草同召集呢份聯署聲明嘅 Peter Daszak，係 EcoHealth Alliance 嘅主席；而 EcoHealth Alliance 又有份向武漢病毒研究所提供項目資金，題目就係冠狀病毒研究。個世界真係細到好似電視劇咁。

05，Lancet 嘅呢篇聯署聲明大大隻字話：we declare no competing interests 。都係嘅，collaborators 嘛，又點算係 competition interests 呢？

06，由疫情擴散至今都成一年有多，究竟有幾多證據顯示，COVID19-SAR2 係純天然無添加呢？答案係零。

... some 15 months after the SARS2 pandemic began, and after a presumably intensive search, Chinese researchers had failed to find either the original bat population, or the intermediate species to which SARS2 might have jumped, or any serological evidence that any Chinese population, including that of Wuhan, had ever been exposed to the virus prior to December 2019. Natural emergence remained a conjecture which, however plausible to begin with, had gained not a shred of supporting evidence in over a year.

07，幾十年後，相信會有人為石正麗寫本傳記。睇中文維基，講到佢係「女蝙蝠俠」，又話佢親自帶隊去雲南採集蝙蝠嘅糞便樣本，研究冠狀病毒。無錯，佢咪就係武漢病毒研究所嘅明星科學家。

08，2015年11月，石正麗連同美國 University of North Caroline 嘅 Ralph Baric，從 SAR1 嘅結構基礎，培植出一隻可以攻擊人類呼吸系統名為 SHC014-CoV 嘅病毒。呢篇文章就話，其實首先 prima facie 嘅證據係：武漢病毒研究所一直有做開 Covid chimera 嘅研究；最少都唔可以排除有泄漏嘅可能。

09，2019年12月，即係疫症爆發前一個月，Peter Daszak 好開興咁接受訪問：「經過六、七年嘅合作研究（講緊石正麗、Ralph Baric） ，我哋發現超過一百隻可以導致 SARS 嘅冠狀病毒；但暫時未有疫苗。」

10，Nicholas Wade 就話，到目前為止，「自然無添加」同「實驗室炮製」兩派睇法，都未有 conclusive 嘅答案；但「自然無添加」就未有任何證據，「實驗室炮製」就最少都有啲表面證供。

11，支持「實驗室炮製」嘅理由：

In all of China, the pandemic broke out on the doorstep of the Wuhan institute. The virus was already well adapted to humans, as expected for a virus grown in humanized mice. It possessed an unusual enhancement, a furin cleavage site, which is not possessed by any other known SARS-related beta-coronavirus, and this site included a double arginine codon also unknown among beta-coronaviruses. What more evidence could you want, aside from the presently unobtainable lab records documenting SARS2’s creation?

12，支持唔住「自然無添加」嘅原因：

No one has found the bat population that was the source of SARS2, if indeed it ever infected bats. No intermediate host has presented itself, despite an intensive search by Chinese authorities that included the testing of 80,000 animals. There is no evidence of the virus making multiple independent jumps from its intermediate host to people, as both the SARS1 and MERS viruses did. There is no evidence from hospital surveillance records of the epidemic gathering strength in the population as the virus evolved. There is no explanation of why a natural epidemic should break out in Wuhan and nowhere else. There is no good explanation of how the virus acquired its furin cleavage site, which no other SARS-related beta-coronavirus possesses, nor why the site is composed of human-preferred codons.

13，Nicholas Wade 好斗膽咁指控以下一干人等：

（1）中國嘅病毒研究人員（不點名石正麗等）；因為有理由相信，佢哋無跟足安全指引。

（2）中國政府；雖然未必係有心整個世紀疫症，但肯定有意隱瞞真相、搬弄世衛、主導輿論、推卸責任、借機抽水⋯⋯

（3）世界各地嘅病毒研究員；圍威喂嘅文化，以科學嘅外衣，掩飾個人關係同利益。

（4）美國政府；EcoHealth Alliance 嘅資金，來自美國政府之下 National Institute of Health 嘅 National Institute of Allergy and Infectious Diseases （NIAID）；而 EcoHealth Alliance 又撥款畀武漢病毒研究所。Wade 話一個咁高風險嘅研究項目，點解可以咁樣外判去第二度？另，Antony Fauci 就係 NIAID 嘅 Director，個世界幾咁細呢。

【延伸閱讀】Lab-Made? SARS-CoV-2 Genealogy Through the Lens of Gain-of-Function Research