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Call for questions: Surgical Oncology (BREAST CANCER). (Patreon)

Published:
2018-07-31 16:47:45
Imported:
2018-07

Content

I’m lucky as hell and scored a sit-down with Dr. Donna-Marie Manasseh, a really revered surgical oncologist in the field of breast cancer. So if you have questions, leave them in the comments and I’ll get to as many as I can! She’s truly an amazing woman and doctor and I HAVE BUTTERFLIES. For real.

Comments

Anna Thompson

Does the make up/shape of your breasts factor in to your risk of getting breast cancer?

I Dreamt a Story (edited)

Comment edits

2026-09-15 06:00 I've heard aluminum in deodorant contributes to breast cancer and other issues. True or false?
2018-07-31 16:52

Becca Bee

As the unhappy owner of a set of lumpy boobs, I get mammograms and ultrasounds on these jerks twice a year. Is there anything else I could do to stay healthy? Is the 6 months between squeezes too much time? Alternately, is there anything I can do to not be terrified for weeks at a time twice a year?

Not-Poignant/Pia Foxhall

How often do you have to go back in after surgery because it turns out the margins were larger than expected? And/or Are the survival rates post breast cancer discovery and treatment increasing? And how long do you measure survival rates post breast cancer treatment?

Anne Simonen

What is the best way to do a home breast check? While getting a very small complex cyst investigated, I was told by ultrasound techs/my doctors that I have very dense breast tissue. Does that change how to do breast checks? What does it change (increased risk for cancer)?

Katie Cobb

I know I'm supposed to self examine after I take my last birth control pill for the month. Is this because breast tissues change throughout cycle? Should I check more often than the same time every month?

Teresa

A few yeard back, there was talk of false positive mammograms and women getting treated unnecessarily. How is detection and treatment changing to ensure women are getting the right tests done at the right times and the right treatments?

Anne Simonen

Another question - I spontaneously developed a large tender lump that didn't end up being anything - the ultrasound tech couldn't even see it on the ultrasound, and it eventually went away. What happened there?

Jane

How have we not developed a better way to screen for cancer than putting our boobs in a honka honka machine??

Anna Thompson

I have very loose/fatty tissue according to my gyno so I have similar questions!

Lara Zielin

Totally! And related to this I wanted to ask about Tomosynthesis machines. Are they really that much better? I just had my first mammogram 2 weeks ago, and the tech was all like, "You might hear back from us and chances are it's a false alarm." I hear Tomosynthesis machines (which I guess do 3D images instead of 2D images) reduce the false alarms, which THANK YOU if they do. Should we ask for Tomosynthesis machines if they're available?

Charlotte Milling

Is there a link between gynecological abnormalities people might experience earlier in life (e.g., endometriosis or PCOS) and propensity to develop breast (or even other gynecological) cancer? Should folks with those disorders consider themselves in the increased risk category and step up their screening or start screening earlier?

Charlotte Milling

Yes!! As a sweaty gal, I feel like I'm forced to make a tradeoff between immediate awkard social conditions and long-term, marginally-increased risk for a condition I might develop anyway!

Charlotte Milling

One last question... can I just cut them off and forego the whole "will I/won't I get breast cancer?" dilemma? I feel like they're more of a burden anyway...

Natasha Bharj

I've seen so many sexist objectifying breast cancer awareness campaigns - what's the professional opinion on this? Is any awareness good or could there be negative downstream effects of bad campaigns? (Other than being gross)

Joe Weinmunson

A friend of mine has idiopathic granulomatous mastitis (her case has been written up in a couple of journals). It seems really mysterious--any thoughts of what causes the condition?

Kira Lichtenfeld

What are your feelings about getting a mastectomy due to inherited gene mutations, specifically BRCA 1 or 2, to reduce the chances later in life? ......asking for a friend....

Brooke Danielle

What, if anything, should I be asking my doctor to check me for regarding breast health, and on what cadence? I do my annual exam every year and that includes the breast exam, but don't know if there's anything else I should be asking for.

antlerlad (edited)

Comment edits

2026-09-15 06:00 I read through the questions, and I'm seeing a lot about birth control and boobies - is there anything people with breasts should know in general about taking birth control? Do they increase breast cancer risks, etc (obviously it's dependent on the medication but You Know)
2018-07-31 17:17

Marisa Brewer

How do you feel about marijuana as a substitute for chemo?

Julie

Questions from my husband: Are there different types of breast cancer, and do they ever occur concurrently between left and right breast, or do people usually get one or the other?  As someone who is less likely to have cells go rogue in that area, I’m a neophyte on this subject.  Does breast cancer ever start as something else first, then spread to the breasts?

Ashley Maniaci

Aside from yearly preventative testing is there anything one can do to prevent breast cancer? Ie: eat antioxidants, keep the cellphone out of the bra (also- is this flim-flam?)

Rachel von Morrigan

It’s become pretty commonplace in OB/GYN offices to be offered testing to determine your risks for cancer in the reproductive organs as well as breast cancer. When I was last in, my gyno explained that if you have a high enough percentage you could have a full hysterectomy or mastectomy. Is this really a good idea? Part of me feels like it’s putting the cart before the horse and spending a boatload of money when it’s not actually necessary. I’m not a doctor though and could be super duper wrong.

Jenny

I have fibroadenoma in both breasts, does this put me at greater risk for breast cancer? I know the lumps are benign (per the biopsy), but can they eventually become cancerous?

Craig Curry

When cutting out cancer how do you know if you got "it all?" It seems like it would be hard to see. Do you take a little of the tissue below it

Anna Mc

Does dense breast tissue make it harder to detect / treat breast cancer? Also, does having previously had a breast reduction (anchor procedure) have any affect on treatment if one later develops breast cancer?

Christin McAdams

I had cervical cancer when I was 24 and had a radical hysterectomy. They left my ovaries to try to preserve fertility in case I wanted to harvest eggs. They told me at that time that my risk for breast cancer was significantly lowered because of my hysterectomy. I always felt like this might be BS they fed to a young girl who was now paranoid about dying. Is there any truth to this?

Anna Mc

Also, I've read conflicting evidence about soy and its affect on breast health. Same goes for hormone / antibiotic treated meat, dairy, and even produce products... Should I just be afraid of everything and start my own farm?

Radha Vakharia

i'd be curious to know if she saw any changes in how people wanted to proceed (or not) with different surgeries in breast cancer after the whole Angelina Jolie thing happened. Like did she see any sort of influence on people's willingness to go for full mastectomies rather than just the surgical removal of the cancerous tissues after a celebrity publicly chose that route?

Becki McClure

I am BRCA2 positive which puts me at a very high risk for Breast Cancer yet significantly lower risk for a ovarian cancer but both my mother (56) and maternal grandmother (63) died of OVCA. Are there any hypotheses as to why OVCA is how my family seems to be impacted...like is there another gene that is pushing odds on the side of ovarian instead of breast. Is it environmental? Just weird coincidence? I participated in Marsha Rivkin Center blood studies for many years until I had a hysterectomy and bilateral oofetectomy at age 40 to reduce my risk. I also had endometriosis and PCOS. I only got pregnant once but lost it to miscarriage. My mother and grandmother carried 3 full term pregnancies but joked that they got pregnant whenever someone looked their way (my mother had 3 significant miscarriages, believe grandmother did as well). I once read that number of times you ovulated in a lifetime increased ovarian cancer odds due to the tissue regeneration that takes place after an egg is expelled from the cyst. Since I rarely ovulated due to pills/pcos/endometriosis would that reduce my OVCA risk? Is my breast cancer risk still crazy high now that I have no more ovaries? Last thing to note. My mother died of OVCA even though she had her ovaries removed after her mother died. At the time (2000) we were told that any ovarian cell left behind could have turned into cancer. Is that true and how should I screen for OVCA now in the absence of ovaries? (I do breast screens every 6 months alternating MRI and Mammogram)

Emilia Ricciuti

My mother had stage 1 breast cancer back in 2012, and one of the ladies she worked with told her that she got cancer because she was stressed out all the time. while this comment made me very concerned for the lack of a filter on this woman's mouth, it also made me concerned that there is some validity to it. does being stressed out all the time give you cancer? (i know correlation does not equal causation but.... still. whats the dealio here?)

Eva

Why do humans have so few copies of the tumor suppressor genes (unlike elephants, per a Nature article a few years ago)? How will genetic engineering and CRISPR influence the future of cancer treatment?

Brianna Joyce

Seems like EVERYONE has been hit by this beast of a cancer (it took my momma in 2008), I’m very excited to hear Dadward’s jokes to brighten the subject! My question: what do we know about how and why cancer becomes metastatic?

Betsy Lang

It is difficult to palpate large breast’s for lumps. Is there any suggestions for that’s?

Billy Marino

I'm also curious about the possibilities of using CRISPR for cancer treatment. I remember seeing a special on HBO's Vice about some successful tests that edited HIV viruses and "reprogrammed" them to attack cancer cells and replace them with healthy cells, but have heard relatively little since then. I'm also not a scientist and am sure I oversimplified the hell out of how that process actually works.

Lauren Harter

When, and how often, should men get their mammaries checked?

DiScribe

Soooo... what differentiates the stages of cancer? And what does that indicate for the patient if anything?

Belinda Kuo

I had a (right boob) mastectomy and they took some (right side) lymph nodes. I've been told that I should never let them take blood from that arm again. True? And why?

Colette Ayers

I know that breasts can get lumps due to hormonal change during menstrstion but how can I tell if it could be cancer or they are just benign and can these mutate into cancerous cells?

Laura Cowles

is there anything to be gained from the Persephone Trial with the use of Herceptin and Perjeta for 6 months vs 12 months? Also, if someone has micro calcifications that show up on a mammogram after completing chemo is that cause for a mastectomy as opposed to a partial mastectomy for breast conservation? What would you say is the largest factor that has changed the way that you personally look at treating patients in the last 10 years? I feel that the world of cancer research and treatment is changing so quickly and it's difficult to figure out what is good information and what is BS, so I'm very interested in knowing what you feel is one of the most significant change you'e seen? Thanks DadWard for getting this one up!!!

Queen Jean

I have a 38-year old friend who was recently diagnosed with Stage 3 breast cancer and then found out that she has the BRCA gene mutation. She underwent a double mastectomy but mentioned that she'll eventually need to get her reproductive organs surgically removed to prevent cancer there. I feel like a dummy asking, but how does the BRCA gene work? What are the recommendations for getting tested for this gene? I have another friend (early 40's) who was diagnosed with double-negative breast cancer a few years ago. Fortunately, she's currently cancer free but that sounded like a scary diagnosis. What exactly is double-negative breast cancer? And is it odd that a woman in her late 30's knows so many people in their late 30's/early 40's who have been diagnosed with breast cancer? It feels like it is all around me and I'm terrified.

Kennedy

Also, how exactly do you get tested for the BRCA gene? Is it bloodwork? Or some other kind of test? What is the process like?

Katie Trivilino

I have a friend who wants to go into veterinary oncology. What are some similarities and differences between oncology in humans and in animals?

Kelli Brockington

OK - I have the double whammy - My Mother In Law was diagnosed with breast cancer in 1990 - Just when I found out I was pregnant with her 1st grandchild. Luckily - she fought the good fight for 20 years - so both my son & daughter got to know their Granby. Unfortunately - it stigmatized to her lungs 1st (successful defeat of that) then in her liver - which she would have won if she had not developed early onset dementia & we lost her in 2011 - on the same fucking day as my sister in laws sister to ovarian cancer & Steve Jobs to whatever cancer he was in denial about.- then last year - July - my 80 yr old mom was diagnosed with Invasive Ductal Carcinoma. ARRGH. Luckily for her - he goes to the doctor regularly & they fond it very early - stage 1 lumpectomy & no lymph nodes were affected. and now 1 year later still cancer free.

Kelli Brockington

Neither families had breast cancer in its history - why does it show up?

Kelli Brockington

Now me & my 3 sisters, my daughter (both maternal & paternal sides), 3 nieces & 3 grand nieces have to check the cancer info on medical forms. boooo!

Kelli Brockington

And I am wearing my Ask Smart People Stupid Questions tshirt today!